Whole-Genome Sequencing for National Surveillance of Shiga Toxin–ProducingEscherichia coliO157 | Zendy

Timothy J. Dallman | Zendy; Lisa Byrne | Zendy; Philip Ashton | Zendy; Lauren A. Cowley | Zendy; Neil Perry | Zendy; Goutam K. Adak | Zendy; Liljana Petrovska | Zendy; Richard J. Ellis | Zendy; Richard Elson | Zendy; Anthony Underwood | Zendy; Jonathan Green | Zendy; William P. Hanage | Zendy; Claire Jenkins | Zendy; Kathie Grant | Zendy; John Wain | Zendy

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Whole-Genome Sequencing for National Surveillance of Shiga Toxin–ProducingEscherichia coliO157

Author(s) -

Timothy J. Dallman,

Lisa Byrne,

Philip Ashton,

Lauren A. Cowley,

Neil Perry,

Goutam K. Adak,

Liljana Petrovska,

Richard J. Ellis,

Richard Elson,

Anthony Underwood,

Jonathan Green,

William P. Hanage,

Claire Jenkins,

Kathie Grant,

John Wain

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ318

Subject(s) - multiple loci vntr analysis , variable number tandem repeat , outbreak , whole genome sequencing , typing , pathogenicity island , context (archaeology) , public health surveillance , phylogenetic tree , biology , genome , public health , genetics , medicine , virology , gene , paleontology , allele , nursing

National surveillance of gastrointestinal pathogens, such as Shiga toxin-producing Escherichia coli O157 (STEC O157), is key to rapidly identifying linked cases in the distributed food network to facilitate public health interventions. In this study, we used whole-genome sequencing (WGS) as a tool to inform national surveillance of STEC O157 in terms of identifying linked cases and clusters and guiding epidemiological investigation.

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