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Previous studies indicate that vancomycin is inferior to beta-lactams for treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections. However, it is unclear if this association is true for empiric and definitive therapy. Here, we compared beta-lactams with vancomycin for empiric and definitive therapy of MSSA bloodstream infections among patients admitted to 122 hospitals.

clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)

Comparative Effectiveness of Beta-Lactams Versus Vancomycin for Treatment of Methicillin-Susceptible<i>Staphylococcus aureus</i>Bloodstream Infections Among 122 Hospitals

Comparative Effectiveness of Beta-Lactams Versus Vancomycin for Treatment of Methicillin-SusceptibleStaphylococcus aureusBloodstream Infections Among 122 Hospitals