Good Syndrome: An Adult-Onset Immunodeficiency Remarkable for Its High Incidence of Invasive Infections and Autoimmune Complications
Author(s) -
Marion Malphettes,
Laurence Gérard,
Lionel Galicier,
David Boutboul,
Bouchra Asli,
Raphaël Szalat,
Antoinette Perlat,
A. Masseau,
N. Schleinitz,
G. Le Guenno,
JeanFrançois Viallard,
Bernard Bonnotte,
M.F. Thiercelin-Legrand,
Laurence Sanhès,
Raphaël Borie,
Sophie GeorginLavialle,
Claire Fieschi,
Éric Oksenhendler
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ269
Subject(s) - medicine , incidence (geometry) , immunodeficiency , human immunodeficiency virus (hiv) , immunopathology , immunology , pediatrics , immune system , physics , optics
Good syndrome (GS) is a rare condition in which thymoma is associated with hypogammaglobulinemia. It is characterized by increased susceptibility to bacterial, viral, and fungal infections, as well as autoimmunity. Most patients have no circulating B cells.
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