Neurological Manifestations in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)–Infected Individuals Without HTLV-1–Associated Myelopathy/Tropical Spastic Paraparesis: A Longitudinal Cohort Study | Zendy

Davi Tanajura | Zendy; Néviton Castro | Zendy; Paulo Oliveira | Zendy; Abraão Neto | Zendy; André Muniz | Zendy; Natália B. Carvalho | Zendy; Glória Orge | Zendy; Silvane Santos | Zendy; Marshall J. Glesby | Zendy; Edgar M. Carvalho | Zendy

Open Access

Neurological Manifestations in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)–Infected Individuals Without HTLV-1–Associated Myelopathy/Tropical Spastic Paraparesis: A Longitudinal Cohort Study

Author(s) -

Davi Tanajura,

Néviton Castro,

Paulo Oliveira,

Abraão Neto,

André Muniz,

Natália B. Carvalho,

Glória Orge,

Silvane Santos,

Marshall J. Glesby,

Edgar M. Carvalho

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ229

Subject(s) - medicine , tropical spastic paraparesis , myelopathy , incidence (geometry) , hyperreflexia , cohort , cumulative incidence , human t lymphotropic virus , pediatrics , cohort study , peripheral neuropathy , surgery , spinal cord , physics , psychiatry , optics , diabetes mellitus , endocrinology

Human T-cell lymphotropic virus type 1 (HTLV-1) is the agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), observed in up to 5% of infected individuals. Despite low prevalence, many HTLV-1-infected patients who do not fulfill criteria for HAM/TSP present with neurological complaints related to sensory, motor, urinary, or autonomic manifestations. The aim of this study was to determine the incidence of neurologic manifestations and risk factors associated with these outcomes.

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