Treatment to Prevent HIV Transmission in Serodiscordant Couples in Henan, China, 2006 to 2012
Author(s) -
M. Kumi Smith,
Daniel Westreich,
Huixin Liu,
Lin Zhu,
Lan Wang,
Wensheng He,
Jianping Zhou,
William C. Miller,
Myron S. Cohen,
Ning Wang
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ200
Subject(s) - serodiscordant , medicine , seroconversion , hazard ratio , cohort , confidence interval , demography , proportional hazards model , cumulative incidence , transmission (telecommunications) , cohort study , incidence (geometry) , immunology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , physics , optics , sociology , electrical engineering , engineering
Antiretroviral therapy (ART) administered in clinical trial settings virtually eliminates the sexual transmission of human immunodeficiency virus (HIV) in serodiscordant couples, but effectiveness of treatment as prevention in the community is debated. Conflicting results from previous analyses in a Chinese cohort underscore the importance of determining effectiveness of ART delivered in resource limited settings.
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