Comparison of the Metabolic Effects of Ritonavir-Boosted Darunavir or Atazanavir Versus Raltegravir, and the Impact of Ritonavir Plasma Exposure: ACTG 5257 | Zendy

Ighovwerha Ofotokun | Zendy; Lumine H Na | Zendy; Raphael J. Landovitz | Zendy; Heather J. Ribaudo | Zendy; Grace A. McComsey | Zendy; Catherine Godfrey | Zendy; Francesca Aweeka | Zendy; Susan E. Cohn | Zendy; Manish Sagar | Zendy; Daniel R. Kuritzkes | Zendy; Todd T. Brown | Zendy; Kristine B. Patterson | Zendy; Michael F. Para | Zendy; Randi Y. Leavitt | Zendy; Angelina Villası́s-Keever | Zendy; Bryan Baugh | Zendy; Jeffrey L. Lennox | Zendy; Judith S. Currier | Zendy

Open Access

Comparison of the Metabolic Effects of Ritonavir-Boosted Darunavir or Atazanavir Versus Raltegravir, and the Impact of Ritonavir Plasma Exposure: ACTG 5257

Author(s) -

Ighovwerha Ofotokun,

Lumine H Na,

Raphael J. Landovitz,

Heather J. Ribaudo,

Grace A. McComsey,

Catherine Godfrey,

Francesca Aweeka,

Susan E. Cohn,

Manish Sagar,

Daniel R. Kuritzkes,

Todd T. Brown,

Kristine B. Patterson,

Michael F. Para,

Randi Y. Leavitt,

Angelina Villası́s-Keever,

Bryan Baugh,

Jeffrey L. Lennox,

Judith S. Currier

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ193

Subject(s) - darunavir , ritonavir , raltegravir , atazanavir , medicine , cart , pharmacology , regimen , human immunodeficiency virus (hiv) , antiretroviral therapy , viral load , virology , mechanical engineering , engineering

Metabolic effects following combination antiretroviral therapy (cART) vary by regimen type. Changes in metabolic effects were assessed following cART in the AIDS Clinical Trials Group (ACTG) A5257 study, and correlated with plasma ritonavir trough concentrations (C24).

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