In Vivo Horizontal Gene Transfer of the Carbapenemase OXA-48 During a Nosocomial Outbreak | Zendy

Stephan Göttig | Zendy; Tobias Gruber | Zendy; Bärbel Stecher | Zendy; Thomas A. Wichelhaus | Zendy; Volkhard A. J. Kempf | Zendy

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In Vivo Horizontal Gene Transfer of the Carbapenemase OXA-48 During a Nosocomial Outbreak

Author(s) -

Stephan Göttig,

Tobias Gruber,

Bärbel Stecher,

Thomas A. Wichelhaus,

Volkhard A. J. Kempf

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ191

Subject(s) - galleria mellonella , klebsiella pneumoniae , in vivo , microbiology and biotechnology , escherichia coli , plasmid , multilocus sequence typing , horizontal gene transfer , biology , outbreak , typing , in vitro , virology , gene , virulence , genetics , phylogenetic tree , genotype

OXA-48 is a highly prevalent carbapenemase and has been isolated worldwide. Here, we investigate the in vivo horizontal gene transfer (HGT) of blaOXA-48 from Klebsiella pneumoniae to Escherichia coli in an infected patient.

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