Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated With Virologic Failure: Results From the Multinational PEARLS (ACTG A5175) Clinical Trial | Zendy

Rami Kantor | Zendy; Laura Smeaton | Zendy; Saran Vardhanabhuti | Zendy; Sarah E. Hudelson | Zendy; Carole L. Wallis | Zendy; Srikanth Tripathy | Zendy; Mariza Gonçalves Morgado | Zendy; Shanmugam Saravanan | Zendy; Pachamuthu Balakrishnan | Zendy; Marissa B Reitsma | Zendy; Stephen A. Hart | Zendy; John W. Mellors | Zendy; Elias K. Halvas | Zendy; Beatriz Grinsztejn | Zendy; Mina C. Hosseinipour | Zendy; Johnstone Kumwenda | Zendy; Alberto La Rosa | Zendy; Umesh Lalloo | Zendy; Javier R. Lama | Zendy; Mohammed Rassool | Zendy; Breno Santos | Zendy; Khuanchai Supparatpinyo | Zendy; James Hakim | Zendy; Timothy Flanigan | Zendy; Nagalingeswaran Kumarasamy | Zendy; Thomas Campbell | Zendy; Susan H. Eshleman | Zendy

Open Access

Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated With Virologic Failure: Results From the Multinational PEARLS (ACTG A5175) Clinical Trial

Author(s) -

Rami Kantor,

Laura Smeaton,

Saran Vardhanabhuti,

Sarah E. Hudelson,

Carole L. Wallis,

Srikanth Tripathy,

Mariza Gonçalves Morgado,

Shanmugam Saravanan,

Pachamuthu Balakrishnan,

Marissa B Reitsma,

Stephen A. Hart,

John W. Mellors,

Elias K. Halvas,

Beatriz Grinsztejn,

Mina C. Hosseinipour,

Johnstone Kumwenda,

Alberto La Rosa,

Umesh Lalloo,

Javier R. Lama,

Mohammed Rassool,

Breno Santos,

Khuanchai Supparatpinyo,

James Hakim,

Timothy Flanigan,

Nagalingeswaran Kumarasamy,

Thomas Campbell,

Susan H. Eshleman

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ102

Subject(s) - medicine , hazard ratio , hiv drug resistance , viral load , genotyping , proportional hazards model , confidence interval , drug resistance , human immunodeficiency virus (hiv) , genotype , immunology , gastroenterology , antiretroviral therapy , biochemistry , biology , microbiology and biotechnology , gene , chemistry

Evaluation of pretreatment HIV genotyping is needed globally to guide treatment programs. We examined the association of pretreatment (baseline) drug resistance and subtype with virologic failure in a multinational, randomized clinical trial that evaluated 3 antiretroviral treatment (ART) regimens and included resource-limited setting sites.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research