Nasal Inoculation of the Commensal Neisseria lactamica Inhibits Carriage of Neisseria meningitidis by Young Adults: A Controlled Human Infection Study | Zendy

Alice M. Deasy | Zendy; Ed Guccione | Zendy; Adam P. Dale | Zendy; Nick Andrews | Zendy; Cariad Evans | Zendy; Julia S. Bennett | Zendy; Holly B. Bratcher | Zendy; Martin Maiden | Zendy; Andrew Gorringe | Zendy; Robert C. Read | Zendy

Open Access

Nasal Inoculation of the Commensal Neisseria lactamica Inhibits Carriage of Neisseria meningitidis by Young Adults: A Controlled Human Infection Study

Author(s) -

Alice M. Deasy,

Ed Guccione,

Adam P. Dale,

Nick Andrews,

Cariad Evans,

Julia S. Bennett,

Holly B. Bratcher,

Martin Maiden,

Andrew Gorringe,

Robert C. Read

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ098

Subject(s) - neisseria meningitidis , carriage , microbiology and biotechnology , neisseriaceae , medicine , meningococcal disease , meningococcal vaccine , colonization , neisseria , population , virology , biology , antibiotics , bacteria , genetics , environmental health , pathology

Herd protection by meningococcal vaccines is conferred by population-level reduction of meningococcal nasopharyngeal colonization. Given the inverse epidemiological association between colonization by commensal Neisseria lactamica and meningococcal disease, we investigated whether controlled infection of human volunteers with N. lactamica prevents colonization by Neisseria meningitidis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research