Increased Risk for and Mortality From Invasive Pneumococcal Disease in HIV-Exposed but Uninfected Infants Aged <1 Year in South Africa, 2009–2013
Author(s) -
Claire von Mollendorf,
Anne von Gottberg,
Stefano Tempia,
Susan Meiring,
Linda de Gouveia,
Vanessa Quan,
Sarona Lengana,
Theunis Avenant,
Nicolette du Plessis,
Brian Eley,
Heather Finlayson,
Gary Reubenson,
Mamokgethi Moshe,
Katherine L. O’Brien,
Keith P. Klugman,
Cynthia G. Whitney,
Cheryl Cohen
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ059
Subject(s) - medicine , case fatality rate , population , incidence (geometry) , pediatrics , transmission (telecommunications) , confidence interval , seroprevalence , epidemiology , environmental health , immunology , antibody , serology , electrical engineering , optics , engineering , physics
High antenatal human immunodeficiency virus (HIV) seroprevalence rates (∼ 30%) with low perinatal HIV transmission rates (2.5%), due to HIV prevention of mother-to-child transmission program improvements in South Africa, has resulted in increasing numbers of HIV-exposed but uninfected (HEU) children. We aimed to describe the epidemiology of invasive pneumococcal disease (IPD) in HEU infants.
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