High Frequency of Active HCV Infection Among Seropositive Cases in West Africa and Evidence for Multiple Transmission Pathways
Author(s) -
Jennifer E. Layden,
Richard Odame Phillips,
Shirley OwusuOfori,
Fred Stephen Sarfo,
Stephanie Kliethermes,
Nallely Mora,
Dorcas Owusu,
Kenrad E. Nelson,
Ohene OpareSem,
Lara R. Dugas,
Amy Luke,
David A. Shoham,
Joseph C. Forbi,
Yury Khudyakov,
Richard Cooper
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu965
Subject(s) - medicine , viremia , transmission (telecommunications) , hepatitis c virus , coinfection , serology , immunology , hepatitis c , demography , virus , antibody , electrical engineering , sociology , engineering
Sub-Saharan Africa (SSA) has one of the highest global hepatitis C virus (HCV) prevalence estimates. However, reports that suggest high rates of serologic false positives and low levels of viremia have led to uncertainty regarding the burden of active infection in this region. Additionally, little is known about the predominant transmission risk factors in SSA.
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