Reduced Rotavirus Vaccine Effectiveness Among Children Born During the Rotavirus Season: A Pooled Analysis of 5 Case-Control Studies From the Americas | Zendy

Prasanna Samuel Premkumar | Zendy; Umesh D. Parashar | Zendy; Paul A. Gastañaduy | Zendy; John P. McCracken | Zendy; Lúcia Helena de Oliveira | Zendy; Daniel C. Payne | Zendy; Manish M. Patel | Zendy; Jacqueline E. Tate | Zendy; Ben Lopman | Zendy

Open Access

Reduced Rotavirus Vaccine Effectiveness Among Children Born During the Rotavirus Season: A Pooled Analysis of 5 Case-Control Studies From the Americas

Author(s) -

Prasanna Samuel Premkumar,

Umesh D. Parashar,

Paul A. Gastañaduy,

John P. McCracken,

Lúcia Helena de Oliveira,

Daniel C. Payne,

Manish M. Patel,

Jacqueline E. Tate,

Ben Lopman

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu956

Subject(s) - rotavirus , medicine , rotavirus vaccine , pediatrics , reoviridae , virology , environmental health , virus

Using data from rotavirus vaccine effectiveness (VE) studies, we assessed whether rotavirus season modifies rotavirus VE in infants. In the first year of life, adjusted VE was 72% for children born during rotavirus season and 84% for children born in other months (P = .01). Seasonal factors may interfere with vaccine performance.

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