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Pseudomonas aeruginosa in Cystic Fibrosis Patients With G551D-CFTR Treated With Ivacaftor
Author(s) -
Sonya L. Heltshe,
Nicole Mayer-Hamblett,
Jane L. Burns,
Umer Khan,
Arthur Baines,
Bonnie W. Ramsey,
Steven M. Rowe
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu944
Subject(s) - ivacaftor , cystic fibrosis , medicine , pseudomonas aeruginosa , respiratory system , mutation , cystic fibrosis transmembrane conductance regulator , microbiology and biotechnology , bacteria , gene , genetics , biology
Ivacaftor improves outcomes in cystic fibrosis (CF) patients with the G551D mutation; however, effects on respiratory microbiology are largely unknown. This study examines changes in CF respiratory pathogens with ivacaftor and correlates them with baseline characteristics and clinical response.

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