Serum Galactomannan Versus a Combination of Galactomannan and Polymerase Chain Reaction-Based Aspergillus DNA Detection for Early Therapy of Invasive Aspergillosis in High-Risk Hematological Patients: A Randomized Controlled Trial
Author(s) -
José María Aguado,
Lourdes Vázquez,
Mario FernándezRuiz,
Teresa Villaescusa,
Isabel RuizCamps,
Pere Barba,
J. T. Silva,
Montserrat Batlle,
Carlos Solano,
David Gallardo,
Inmaculada Heras,
Marta Polo,
Rosario Varela,
Cantarero Vallejo,
Teresa Olavé,
Javier LópezJiménez,
M Rovira,
Rocío Parody,
Manuel CuencaEstrella,
Marta Polo Zarzuela,
Fredman González,
P. M. Amador,
Juan Diego Mediavilla,
I. R. Camps,
Nerea Castillo,
María Teresa Martín-Gómez,
J. A. Soriano,
Inmaculada Heras Fernando,
Cristina CastillaLlorente,
R. Cesteros,
M. R. Rodríguez Mondéjar,
Dolores Caballero,
José E. García,
Ignacio García,
Sara de la Mano González,
José María Fernández García-Hierro,
Mar Tormo,
D. Navarro,
Million Molla,
Avelino J. González,
Sónia González,
A. P. Gonzalez,
P. Palomo,
Rocío Parody Porras,
Raquel Sanchez,
María Teresa Olave Rubio,
J. L. Jiménez,
Montserrat Rovira Tarrats,
Michele Grande,
Francisco FernándezAvilés,
María José Buitrago,
T. M. Amador,
Leticia BernalMartínez
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu833
Subject(s) - galactomannan , aspergillosis , medicine , polymerase chain reaction , aspergillus , randomized controlled trial , immunology , gastroenterology , microbiology and biotechnology , biology , gene , biochemistry
The benefit of the combination of serum galactomannan (GM) assay and polymerase chain reaction (PCR)-based detection of serum Aspergillus DNA for the early diagnosis and therapy of invasive aspergillosis (IA) in high-risk hematological patients remains unclear.
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