Prevention of Anti-Tumor Necrosis Factor-Associated Tuberculosis: A 10-Year Longitudinal Cohort Study | Zendy

Laura Muñoz | Zendy; Susana Boluda | Zendy; Xavier Juanola | Zendy; X. Bordas | Zendy; Cristina Martínez | Zendy; Miguel Santín | Zendy

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Prevention of Anti-Tumor Necrosis Factor-Associated Tuberculosis: A 10-Year Longitudinal Cohort Study

Author(s) -

Laura Muñoz,

Susana Boluda,

Xavier Juanola,

X. Bordas,

Cristina Martínez,

Miguel Santín

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu796

Subject(s) - medicine , tuberculosis , cohort study , cohort , tumor necrosis factor alpha , risk factor , oncology , immunology , pathology

The extent to which anti-tumor necrosis factor (TNF)-associated tuberculosis can be prevented is unclear, and there is no established guidance on the optimal screening strategy for latent tuberculosis (LTBI) in patients about to start anti-TNF therapy. We aimed to determine the effectiveness of a comprehensive program for the prevention of anti-TNF-associated tuberculosis, and to evaluate 3 LTBI screening strategies and the need for retesting patients with negative results at baseline.

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