Near-Elimination of Otitis Media Caused by 13-Valent Pneumococcal Conjugate Vaccine (PCV) Serotypes in Southern Israel Shortly After Sequential Introduction of 7-Valent/13-Valent PCV | Zendy

Shalom BenShimol | Zendy; Noga GivonLavi | Zendy; Eugene Leibovitz | Zendy; SIMON RAIZ | Zendy; David Greenberg | Zendy; Ron Dagan | Zendy

Open Access

Near-Elimination of Otitis Media Caused by 13-Valent Pneumococcal Conjugate Vaccine (PCV) Serotypes in Southern Israel Shortly After Sequential Introduction of 7-Valent/13-Valent PCV

Author(s) -

Shalom BenShimol,

Noga GivonLavi,

Eugene Leibovitz,

SIMON RAIZ,

David Greenberg,

Ron Dagan

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu683

Subject(s) - pneumococcal conjugate vaccine , medicine , streptococcus pneumoniae , otitis , incidence (geometry) , serotype , pediatrics , population , confidence interval , pneumococcal infections , virology , surgery , microbiology and biotechnology , antibiotics , environmental health , biology , physics , optics

Otitis media (OM) is common in early childhood. Streptococcus pneumoniae caused approximately 30%-60% of episodes before the pneumococcal conjugate vaccine (PCV) era. The 7-valent PCV (PCV7) was introduced to the Israeli National Immunization Plan in July 2009, and was gradually replaced by the 13-valent PCV (PCV13) starting in November 2010. We aimed at assessing the impact of PCV7/PCV13 sequential introduction on pneumococcal and overall OM necessitating middle ear fluid culture in children aged <2 years in southern Israel.

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