Valley Fever: Finding New Places for an Old Disease: Coccidioides immitis Found in Washington State Soil Associated With Recent Human Infection
Author(s) -
Anastasia P. Litvintseva,
Nicola Marsden-Haug,
Steven F. Hurst,
Heather Hill,
Lalitha Gade,
Elizabeth M. Driebe,
C Ralston,
Chandler C. Roe,
Bridget M. Barker,
Marcia Goldoft,
Paul Keim,
Ron Wohrle,
George R. Thompson,
David M. Engelthaler,
Mary E. Brandt,
Tom Chiller
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu681
Subject(s) - coccidioides immitis , medicine , coccidioides , disease , virology , immunology , microbiology and biotechnology , pathology , biology , dermatology
We used real-time polymerase chain reaction and culture to demonstrate persistent colonization of soils by Coccidioides immitis, an agent of valley fever, in Washington State linked to recent human infections and located outside the endemic range. Whole-genome sequencing confirmed genetic identity between isolates from soil and one of the case-patients.
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