Telaprevir for HIV/Hepatitis C Virus-Coinfected Patients Failing Treatment With Pegylated Interferon/Ribavirin (ANRS HC26 TelapreVIH): An Open-Label, Single-Arm, Phase 2 Trial
Author(s) -
L. Cotte,
Joerg E. Braun,
C. Lascoux-Combe,
Corine Vincent,
MarcAntoine Valantin,
P. Sogni,
Karine Lacombe,
D. Neau,
H. Aumaitre,
Dominique Batisse,
P. de Truchis,
A. Gervais,
C. Michelet,
Philippe Morlat,
Daniel Vittecoq,
Isabelle Rosa,
Inga Bertucci,
Stéphane Chevaliez,
J.-P. Aboulker,
JeanMichel Molina,
Lise Bernard,
Arnaud Chéret,
Laurent Cotte,
P. Dellamonica,
Stéphanie Dominguez,
Pierre Marie Girard,
F. Lucht,
Sophie Métivier,
GeorgesPhilippe Pageaux,
Stanislas Pol,
Eric S. Rosenthal,
David Zucman
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu659
Subject(s) - medicine , ribavirin , pegylated interferon , telaprevir , efavirenz , emtricitabine , population , hepatitis c virus , virology , gastroenterology , regimen , hepatitis c , viral load , lamivudine , hepatitis b virus , virus , environmental health , antiretroviral therapy
Retreatment with pegylated interferon (peg-IFN) and ribavirin (RBV) results in poor sustained virological response (SVR) rates in human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patients. There are limited data regarding the use of telaprevir plus peg-IFN/RBV in this population.
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