High Usage of Topical Fusidic Acid and Rapid Clonal Expansion of Fusidic Acid–Resistant Staphylococcus aureus: A Cautionary Tale | Zendy

Deborah A. Williamson | Zendy; Stefan Monecke | Zendy; Helen Heffernan | Zendy; Stephen Ritchie | Zendy; Sally Roberts | Zendy; Arlo Upton | Zendy; Mark Thomas | Zendy; John D. Fraser | Zendy

Open Access

High Usage of Topical Fusidic Acid and Rapid Clonal Expansion of Fusidic Acid–Resistant Staphylococcus aureus: A Cautionary Tale

Author(s) -

Deborah A. Williamson,

Stefan Monecke,

Helen Heffernan,

Stephen Ritchie,

Sally Roberts,

Arlo Upton,

Mark Thomas,

John D. Fraser

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu658

Subject(s) - fusidic acid , staphylococcus aureus , medicine , microbiology and biotechnology , staphylococcal infections , micrococcaceae , antimicrobial , methicillin resistant staphylococcus aureus , antibiotic resistance , antibiotics , antibacterial agent , dermatology , bacteria , biology , genetics

Our aim was to assess national prescribing trends and determine longitudinal resistance patterns for topical antimicrobials in New Zealand. We observed a dramatic increase in fusidic acid (FA) resistance, and clonal expansion of FA-resistant Staphylococcus aureus. This increase was concurrent with a significant national increase in topical FA dispensing.

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