Impact of GeneXpert MTB/RIF Assay on Triage of Respiratory Isolation Rooms for Inpatients With Presumed Tuberculosis: A Hypothetical Trial | Zendy

Lelia H. Chaisson | Zendy; Marguerite Roemer | Zendy; David Cantú de León | Zendy; Barbara Haller | Zendy; Alexander J. Millman | Zendy; Adithya Cattamanchi | Zendy; J. Lucian Davis | Zendy

Open Access

Impact of GeneXpert MTB/RIF Assay on Triage of Respiratory Isolation Rooms for Inpatients With Presumed Tuberculosis: A Hypothetical Trial

Author(s) -

Lelia H. Chaisson,

Marguerite Roemer,

David Cantú de León,

Barbara Haller,

Alexander J. Millman,

Adithya Cattamanchi,

J. Lucian Davis

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu620

Subject(s) - genexpert mtb/rif , medicine , tuberculosis , isolation (microbiology) , triage , tuberculosis diagnosis , mycobacterium tuberculosis , intensive care medicine , emergency medicine , pathology , microbiology and biotechnology , biology

Placing inpatients with presumed active pulmonary tuberculosis in respiratory isolation pending results of serial sputum acid-fast bacilli (AFB) smear microscopy is standard practice in high-income countries. However, this diagnostic strategy is slow and yields few tuberculosis diagnoses. We sought to determine if replacing microscopy with the GeneXpert MTB/RIF (Xpert) nucleic acid amplification assay could reduce testing time and usage of isolation rooms.

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