Antibiotic-Resistant Gram-Negative Bacterial Infections in Patients With Cancer | Zendy

Federico Pérez | Zendy; Javier A. Adachi | Zendy; Robert A. Bonomo | Zendy

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Antibiotic-Resistant Gram-Negative Bacterial Infections in Patients With Cancer

Author(s) -

Federico Pérez,

Javier A. Adachi,

Robert A. Bonomo

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu612

Subject(s) - stenotrophomonas maltophilia , acinetobacter baumannii , medicine , klebsiella pneumoniae , pseudomonas aeruginosa , antibiotics , microbiology and biotechnology , antibiotic resistance , acinetobacter , gram negative bacteria , stenotrophomonas , klebsiella , escherichia coli , bacteria , pseudomonas , biology , biochemistry , genetics , gene

Patients with cancer are at high risk for infections caused by antibiotic resistant gram-negative bacteria. In this review, we summarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant gram-negative bacterial infection in patients with malignancy, with special attention to carbapenem and expanded-spectrum β-lactam resistance in Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia--all major threats to our cancer patients. Optimal therapy for these antibiotic-resistant pathogens still remains to be determined.

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