Open AccessEmerging Trends of HIV Drug Resistance in Chinese HIV-Infected Patients Receiving First-Line Highly Active Antiretroviral Therapy: A Systematic Review and Meta-Analysis
Author(s) -
Huixin Liu,
Yong Ma,
Yingying Su,
M. Kumi Smith,
Ying Li,
Yinlong Jin,
Hongqiu Gu,
Jing Wu,
Lin Zhu,
Ning Wang
Publication year - 2014
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu590
Subject(s) - medicine , didanosine , confidence interval , meta analysis , regimen , viral load , drug resistance , hiv drug resistance , antiretroviral therapy , immunology , human immunodeficiency virus (hiv) , biology , microbiology and biotechnology
Highly active antiretroviral therapy (HAART) has led to a dramatic decrease in AIDS-related morbidity and mortality through sustained suppression of human immunodeficiency virus (HIV) replication and reconstitution of the immune response. Settings like China that experienced rapid HAART rollout and relatively limited drug selection face considerable challenges in controlling HIV drug resistance (DR).