Immunogenicity of Intradermal Trivalent Influenza Vaccine With Topical Imiquimod: A Double Blind Randomized Controlled Trial | Zendy

Ivan FanNgai Hung | Zendy; Anna J. Zhang | Zendy; Kelvin KaiWang To | Zendy; Jasper FukWoo Chan | Zendy; Can Li | Zendy; Houshun Zhu | Zendy; Patrick Li | Zendy; Clara Li | Zendy; Tuen-Ching Chan | Zendy; Vincent ChiChung Cheng | Zendy; KwokHung Chan | Zendy; KwokYung Yuen | Zendy

Open Access

Immunogenicity of Intradermal Trivalent Influenza Vaccine With Topical Imiquimod: A Double Blind Randomized Controlled Trial

Author(s) -

Ivan FanNgai Hung,

Anna J. Zhang,

Kelvin KaiWang To,

Jasper FukWoo Chan,

Can Li,

Houshun Zhu,

Patrick Li,

Clara Li,

Tuen-Ching Chan,

Vincent ChiChung Cheng,

KwokHung Chan,

KwokYung Yuen

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu582

Subject(s) - medicine , seroconversion , imiquimod , immunogenicity , influenza vaccine , vaccination , hemagglutination assay , antibody titer , immunology , titer , antibody

Imiquimod, a synthetic Toll-like receptor 7 agonist enhanced immunogenicity of influenza vaccine in a mouse model. We hypothesized that topical imiquimod before intradermal influenza vaccination (TIV) would produce similar effect in human.

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