Dramatic Decline of Respiratory Illness Among US Military Recruits After the Renewed Use of Adenovirus Vaccines
Author(s) -
Jennifer M. Radin,
Anthony W. Hawksworth,
Patrick J. Blair,
Dennis J. Faix,
Rema Raman,
Kevin L. Russell,
Gregory C. Gray
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu507
Subject(s) - medicine , respiratory illness , respiratory system , military personnel , covid-19 , military medicine , intensive care medicine , immunology , virology , disease , infectious disease (medical specialty) , outbreak , political science , law
In late 2011, after a 12-year hiatus, oral vaccines against adenovirus types 4 (Ad4) and 7 (Ad7) were again produced and administered to US military recruits. This study examined the impact of the new adenovirus vaccines on febrile respiratory illness (FRI) and adenovirus rates and investigated if new serotypes emerged. FRI rates and their associated hospitalizations had markedly risen since vaccine production ceased in 1999.
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