Early Initiation of Combination Antiretroviral Therapy in HIV-1-Infected Newborns Can Achieve Sustained Virologic Suppression With Low Frequency of CD4+ T Cells Carrying HIV in Peripheral Blood | Zendy

Ari Bitnun | Zendy; Lindy Samson | Zendy; TaeWook Chun | Zendy; Fatima Kakkar | Zendy; Jason Brophy | Zendy; Danielle Murray | Zendy; Shawn J. Justement | Zendy; Hugo Soudeyns | Zendy; Mario Ostrowski | Zendy; Shariq Mujib | Zendy; P. Richard Harrigan | Zendy; John Kim | Zendy; Paul Sandstrom | Zendy; Stanley Read | Zendy

Open Access

Early Initiation of Combination Antiretroviral Therapy in HIV-1-Infected Newborns Can Achieve Sustained Virologic Suppression With Low Frequency of CD4+ T Cells Carrying HIV in Peripheral Blood

Author(s) -

Ari Bitnun,

Lindy Samson,

TaeWook Chun,

Fatima Kakkar,

Jason Brophy,

Danielle Murray,

Shawn J. Justement,

Hugo Soudeyns,

Mario Ostrowski,

Shariq Mujib,

P. Richard Harrigan,

John Kim,

Paul Sandstrom,

Stanley Read

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu432

Subject(s) - viremia , cart , medicine , immune system , virology , viral load , immunology , serology , t cell , virus , lentivirus , viral replication , viral disease , antibody , mechanical engineering , engineering

A human immunodeficiency virus type 1 (HIV-1)-infected infant started on combination antiretroviral therapy (cART) at 30 hours of life was recently reported to have no detectable plasma viremia after discontinuing cART. The current study investigated the impact of early cART initiation on measures of HIV-1 reservoir size in HIV-1-infected children with sustained virologic suppression.

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