Mortality Among Tuberculosis Patients With Acquired Resistance to Second-line Antituberculosis Drugs--United States, 1993-2008 | Zendy

Julia Ershova | Zendy; Ekaterina V. Kurbatova | Zendy; Patrick K. Moonan | Zendy; J. Peter Cegielski | Zendy

Open Access

Mortality Among Tuberculosis Patients With Acquired Resistance to Second-line Antituberculosis Drugs--United States, 1993-2008

Author(s) -

Julia Ershova,

Ekaterina V. Kurbatova,

Patrick K. Moonan,

J. Peter Cegielski

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu372

Subject(s) - medicine , tuberculosis , drug resistance , hazard ratio , proportional hazards model , confidence interval , pathology , microbiology and biotechnology , biology

Resistance to second-line antituberculosis drugs (SLDs) severely compromises treatment options of drug-resistant tuberculosis. We assessed the association between acquisition of resistance (AR) to second-line injectable drugs (SLIs) or fluoroquinolones (FQs) and mortality among tuberculosis cases confirmed by positive culture results with available initial and final drug susceptibility test (DST) results.

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