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Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-Lumefantrine Versus Dihydroartemisinin-Piperaquine for the Treatment of Malaria
Author(s) -
Humphrey Wanzira,
Abel Kakuru,
Emmanuel Arinaitwe,
Victor Bigira,
Mary Muhindo,
Melissa D. Conrad,
Philip J. Rosenthal,
Moses R. Kamya,
Jordan W. Tappero,
Grant Dorsey
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu353
Subject(s) - artemether/lumefantrine , piperaquine , malaria , medicine , lumefantrine , artemether , dihydroartemisinin , incidence (geometry) , randomized controlled trial , artemisinin , pediatrics , plasmodium falciparum , immunology , mathematics , geometry
Artemisinin-based combination therapy (ACT) has become the standard of care for the treatment of uncomplicated Plasmodium falciparum malaria. Although several ACT regimens are approved, data guiding optimal choices of ACTs are limited. We compared short- and long-term outcomes in a cohort of young Ugandan children randomized to 2 leading ACTs.

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