Development and Validation of a Clinical Model to Predict the Presence of β-Lactam Resistance in Viridans Group Streptococci Causing Bacteremia in Neutropenic Cancer Patients
Author(s) -
Samuel A. Shelburne,
Robert E. Lasky,
Pranoti Sahasrabhojane,
Jeffrey Tarrand,
Kenneth V. I. Rolston
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu260
Subject(s) - medicine , bacteremia , viridans streptococci , neutropenia , intensive care medicine , microbiology and biotechnology , streptococcus , antibiotics , bacteria , chemotherapy , genetics , biology
Concern for serious infection due to β-lactam-resistant viridans group streptococci (VGS) is a major factor driving empiric use of an anti-gram-positive antimicrobial in patients with febrile neutropenia. We sought to develop and validate a prediction model for the presence of β-lactam resistance in VGS causing bloodstream infection (BSI) in neutropenic patients.
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