Discovery and Validation of Biomarkers to Guide Clinical Management of Pneumonia in African Children | Zendy

Honglei Huang | Zendy; Readon C Ideh | Zendy; Evelyn Gitau | Zendy; Marie L. Thézénas | Zendy; Muminatou Jallow | Zendy; Bernard E. Ebruke | Zendy; Osaretin Chimah | Zendy; Claire Oluwalana | Zendy; Henri Karanja | Zendy; Grant Mackenzie | Zendy; Richard A. Adegbola | Zendy; Dominic Kwiatkowski | Zendy; Benedikt M. Kessler | Zendy; James A. Berkley | Zendy; Stephen R. C. Howie | Zendy; Climent CasalsPascual | Zendy

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Discovery and Validation of Biomarkers to Guide Clinical Management of Pneumonia in African Children

Author(s) -

Honglei Huang,

Readon C Ideh,

Evelyn Gitau,

Marie L. Thézénas,

Muminatou Jallow,

Bernard E. Ebruke,

Osaretin Chimah,

Claire Oluwalana,

Henri Karanja,

Grant Mackenzie,

Richard A. Adegbola,

Dominic Kwiatkowski,

Benedikt M. Kessler,

James A. Berkley,

Stephen R. C. Howie,

Climent CasalsPascual

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu202

Subject(s) - medicine , pneumonia , biomarker , intensive care medicine , biomarker discovery , bacterial pneumonia , immunology , proteomics , biochemistry , chemistry , gene

Pneumonia is the leading cause of death in children globally. Clinical algorithms remain suboptimal for distinguishing severe pneumonia from other causes of respiratory distress such as malaria or distinguishing bacterial pneumonia and pneumonia from others causes, such as viruses. Molecular tools could improve diagnosis and management.

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