Frequent Occurrence of Cytomegalovirus Retinitis During Immune Reconstitution Warrants Regular Ophthalmic Screening in High-Risk Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients | Zendy

Prashant Hiwarkar | Zendy; Eva Gajdošová | Zendy; Waseem Qasim | Zendy; Austen Worth | Zendy; Judith Breuer | Zendy; R. Chiesa | Zendy; Deborah Ridout | Zendy; Clive Edelsten | Zendy; Anthony T. Moore | Zendy; Persis Amrolia | Zendy; Paul Veys | Zendy; K Rao | Zendy

Open Access

Frequent Occurrence of Cytomegalovirus Retinitis During Immune Reconstitution Warrants Regular Ophthalmic Screening in High-Risk Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients

Author(s) -

Prashant Hiwarkar,

Eva Gajdošová,

Waseem Qasim,

Austen Worth,

Judith Breuer,

R. Chiesa,

Deborah Ridout,

Clive Edelsten,

Anthony T. Moore,

Persis Amrolia,

Paul Veys,

K Rao

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu201

Subject(s) - medicine , viremia , cytomegalovirus retinitis , hematopoietic stem cell transplantation , odds ratio , retinitis , cytomegalovirus , transplantation , complication , ganciclovir , betaherpesvirinae , immunology , pediatrics , surgery , human cytomegalovirus , viral disease , herpesviridae , human immunodeficiency virus (hiv) , virus

Although cytomegalovirus (CMV) retinitis (CMVR) is a well-recognized complication after allogeneic hematopoietic stem cell transplantation (HSCT), standard operating procedures for ophthalmic monitoring are variable. In particular, authors perceived a greater risk of CMVR after pediatric HSCT for inherited immunodeficiencies, in patients who often have pretransplantation viremia. This study was therefore performed to identify high-risk pediatric HSCT recipients who would benefit from regular ophthalmic monitoring.

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