The Temporal Dynamics of Relapse and Reinfection Tuberculosis After Successful Treatment: A Retrospective Cohort Study
Author(s) -
Florian M. Marx,
Rory Dunbar,
Donald A. Enarson,
Brian Williams,
Robin M. Warren,
Gian van der Spuy,
Paul D. van Helden,
Nulda Beyers
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu186
Subject(s) - medicine , tuberculosis , retrospective cohort study , cohort , cohort study , tuberculosis control , directly observed therapy , intensive care medicine , pathology
There is increasing evidence from tuberculosis high-burden settings that exogenous reinfection contributes considerably to recurrent disease. However, large longitudinal studies of endogenous reactivation (relapse) and reinfection tuberculosis are lacking. We hypothesize a relationship between relapse vs reinfection and the time between treatment completion and recurrent disease.
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