The Efficacy of Daptomycin Versus Vancomycin for Methicillin-Resistant Staphylococcus aureus Bloodstream Infection in Patients With Impaired Renal Function | Zendy

Allan P. Weston | Zendy; Yoav Golan | Zendy; Christina Holcroft | Zendy; David R. Snydman | Zendy

Open Access

The Efficacy of Daptomycin Versus Vancomycin for Methicillin-Resistant Staphylococcus aureus Bloodstream Infection in Patients With Impaired Renal Function

Author(s) -

Allan P. Weston,

Yoav Golan,

Christina Holcroft,

David R. Snydman

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu165

Subject(s) - daptomycin , medicine , vancomycin , bacteremia , renal function , odds ratio , methicillin resistant staphylococcus aureus , retrospective cohort study , confidence interval , staphylococcus aureus , surgery , antibiotics , microbiology and biotechnology , biology , bacteria , genetics

Concerns regarding the efficacy of daptomycin for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections in patients with impaired renal function are reflected in a recent package insert change by the Food and Drug Administration (FDA). However, this decision was based on a small subgroup analysis and it is unclear if this is a true association.

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