Open AccessThe Efficacy of Daptomycin Versus Vancomycin for Methicillin-Resistant Staphylococcus aureus Bloodstream Infection in Patients With Impaired Renal Function
Author(s) -
Adam Weston,
Yoav Golan,
Christina Holcroft,
David R. Snydman
Publication year - 2014
Publication title -
clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu165
Subject(s) - daptomycin , medicine , vancomycin , bacteremia , renal function , odds ratio , methicillin resistant staphylococcus aureus , retrospective cohort study , confidence interval , staphylococcus aureus , surgery , antibiotics , microbiology and biotechnology , biology , bacteria , genetics
Concerns regarding the efficacy of daptomycin for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections in patients with impaired renal function are reflected in a recent package insert change by the Food and Drug Administration (FDA). However, this decision was based on a small subgroup analysis and it is unclear if this is a true association.