Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study | Zendy

Ilan Youngster | Zendy; Jenny Sauk | Zendy; Christina Pindar | Zendy; Robin Wilson | Zendy; Jess L. Kaplan | Zendy; Mark Smith | Zendy; Eric J. Alm | Zendy; Dirk Gevers | Zendy; George H. Russell | Zendy; Elizabeth Hohmann | Zendy

Open Access

Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study

Author(s) -

Ilan Youngster,

Jenny Sauk,

Christina Pindar,

Robin Wilson,

Jess L. Kaplan,

Mark Smith,

Eric J. Alm,

Dirk Gevers,

George H. Russell,

Elizabeth Hohmann

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu135

Subject(s) - medicine , interquartile range , clostridium difficile , clinical endpoint , colonoscopy , diarrhea , surgery , adverse effect , randomized controlled trial , feces , gastroenterology , antibiotics , colorectal cancer , cancer , microbiology and biotechnology , biology , paleontology

Recurrent Clostridium difficile infection (CDI) with poor response to standard antimicrobial therapy is a growing medical concern. We aimed to investigate the outcomes of fecal microbiota transplant (FMT) for relapsing CDI using a frozen suspension from unrelated donors, comparing colonoscopic and nasogastric tube (NGT) administration.

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