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Birth Prevalence of Congenital Cytomegalovirus Among Infants of HIV-Infected Women on Prenatal Antiretroviral Prophylaxis in South Africa
Author(s) -
Sheetal Manicklal,
Anika M. van Niekerk,
Steve Kroon,
Cecelia Hutto,
Zdeněk Novák,
Sunil Pati,
N. Chowdhury,
NY Hsiao,
Suresh B. Boppana
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu096
Subject(s) - medicine , cytomegalovirus , gestational age , odds ratio , pregnancy , pediatrics , zidovudine , obstetrics , immunology , viral disease , human immunodeficiency virus (hiv) , herpesviridae , biology , genetics
A high rate of congenital cytomegalovirus (CMV) has been documented in human immunodeficiency virus (HIV)-exposed infants in industrialized settings, both in the pre- and post-highly active antiretroviral therapy (HAART) era. Only limited data on the birth prevalence of congenital CMV among infants of HIV-infected women on prenatal antiretroviral (ARV) prophylaxis are available from sub-Saharan Africa, despite a high prevalence of both infections. We evaluated the prevalence of congenital CMV in HIV-exposed infants in the Western Cape, South Africa.

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