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MSG-01: A Randomized, Double-Blind, Placebo-Controlled Trial of Caspofungin Prophylaxis Followed by Preemptive Therapy for Invasive Candidiasis in High-Risk Adults in the Critical Care Setting
Author(s) -
Luis OstroskyZeichner,
Shmuel Shoham,
José A. Vázquez,
Annette C. Reboli,
Robert F. Betts,
Michelle Barron,
Mindy G. Schuster,
Marc A. Judson,
Sanjay G. Revankar,
Juan Pablo Caeiro,
Julie E. Mangino,
David Mushatt,
Roger Bedimo,
Alison G. Freifeld,
M. Hong Nguyen,
Carol A. Kauffman,
William E. Dismukes,
Andrew O. Westfall,
J. B. Deerman,
G. Christopher Wood,
Jack D. Sobel,
Peter G. Pappas
Publication year - 2014
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciu074
Subject(s) - medicine , caspofungin , invasive candidiasis , placebo , randomized controlled trial , intensive care medicine , antifungal , fluconazole , dermatology , alternative medicine , pathology
Invasive candidiasis is the third most common bloodstream infection in the intensive care unit (ICU) and is associated with morbidity and mortality. Prophylaxis and preemptive therapy are attractive strategies for this setting.

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