Lower Pill Burden and Once-Daily Antiretroviral Treatment Regimens for HIV Infection: A Meta-Analysis of Randomized Controlled Trials | Zendy

Jean B. Nachega | Zendy; Jean-Jacques Parienti | Zendy; Olalekan A. Uthman | Zendy; Robert Gross | Zendy; David W. Dowdy | Zendy; Paul E. Sax | Zendy; Joel E. Gallant | Zendy; Michael J. Mugavero | Zendy; Edward J. Mills | Zendy; Thomas P. Giordano | Zendy

Open Access

Lower Pill Burden and Once-Daily Antiretroviral Treatment Regimens for HIV Infection: A Meta-Analysis of Randomized Controlled Trials

Author(s) -

Jean B. Nachega,

Jean-Jacques Parienti,

Olalekan A. Uthman,

Robert Gross,

David W. Dowdy,

Paul E. Sax,

Joel E. Gallant,

Michael J. Mugavero,

Edward J. Mills,

Thomas P. Giordano

Publication year - 2014

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciu046

Subject(s) - medicine , pill , dosing , confidence interval , randomized controlled trial , population , meta analysis , pharmacology , environmental health

Contemporary antiretroviral treatment regimens are simpler than in the past, with lower pill burden and once-daily dosing frequency common. We performed a meta-analysis of randomized controlled trials (RCTs) to investigate the impact of pill burden and once-daily vs twice-daily dosing on ART adherence and virological outcomes.

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