Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit | Zendy

James Price | Zendy; Tanya Golubchik | Zendy; Kevin Cole | Zendy; D. J. Wilson | Zendy; Derrick W. Crook | Zendy; Guy Thwaites | Zendy; Rory Bowden | Zendy; Andrew Walker | Zendy; Tim Peto | Zendy; John R. Paul | Zendy; Martin Llewelyn | Zendy

Open Access

Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit

Author(s) -

James Price,

Tanya Golubchik,

Kevin Cole,

D. J. Wilson,

Derrick W. Crook,

Guy Thwaites,

Rory Bowden,

Andrew Walker,

Tim Peto,

John R. Paul,

Martin Llewelyn

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit807

Subject(s) - staphylococcus aureus , medicine , whole genome sequencing , transmission (telecommunications) , staphylococcal infections , methicillin resistant staphylococcus aureus , genome , typing , intensive care unit , microbiology and biotechnology , intensive care medicine , biology , genetics , bacteria , gene , electrical engineering , engineering

Strategies to prevent Staphylococcus aureus infection in hospitals focus on patient-to-patient transmission. We used whole-genome sequencing to investigate the role of colonized patients as the source of new S. aureus acquisitions, and the reliability of identifying patient-to-patient transmission using the conventional approach of spa typing and overlapping patient stay.

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