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Administration of AS03B-adjuvanted A(H1N1)pdm09 Vaccine in Children Aged <3 Years Enhances Antibody Response to H3 and B Viruses Following a Single Dose of Trivalent Vaccine One Year Later
Author(s) -
Katja Höschler,
Nick Andrews,
Saul N. Faust,
Adam Finn,
Andrew J. Pollard,
Matthew D. Snape,
W. Thomson Walker,
Maria Zambon,
Elizabeth Miller
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit692
Subject(s) - medicine , virology , antibody , influenza vaccine , antibody response , serology , immunology , trivalent influenza vaccine , virus , hemagglutination assay , vaccination , titer
We report on a follow-up clinical and serological investigation of 274 children who received seasonal influenza vaccine (trivalent inactivated vaccine [TIV]) 1 year after receipt of either AS03(B)-adjuvanted subunit or whole virus monovalent A(H1N1)pdm09 vaccine and describe the antibody responses to the H3N2 A/Perth/16/2009 and B/Brisbane/60/2008 components of TIV.

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