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Virological, Serological, and Antiviral Studies in an Imported Human Case of Avian Influenza A(H7N9) Virus in Taiwan
Author(s) -
PiHan Lin,
TaiLing Chao,
ShuennWen Kuo,
JannTay Wang,
ChienChing Hung,
Huan-Chun Lin,
Zong-Yu Yang,
ShuYuan Ho,
ChunKai Chang,
M.B. Huang,
Hui-Hou Chen,
YeeChun Chen,
HongShiee Lai,
SuiYuan Chang,
ShanChwen Chang,
PanChyr Yang
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit638
Subject(s) - medicine , oseltamivir , serology , virology , virus , antibody , influenza a virus subtype h5n1 , influenza a virus , transmission and infection of h5n1 , covid-19 , immunology , avian influenza virus , disease , infectious disease (medical specialty)
We describe the clinical course and virological characteristics of the first H7N9 influenza case in a Taiwanese patient; this patient had detectable viruses in the airway for 2 weeks, during which time an oseltamivir resistance-associated R292K mutation rapidly emerged. Anti-H7N9 antibody was detected 21 days after onset of symptoms, when H7N9 viral load declined significantly.

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