Congenital Cytomegalovirus Infection: Clinical Outcome
Author(s) -
Suresh B. Boppana,
Shan Ross,
Karen B. Fowler
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit629
Subject(s) - medicine , asymptomatic , cytomegalovirus , pediatrics , human cytomegalovirus , cytomegalovirus infections , betaherpesvirinae , intensive care medicine , immunology , herpesviridae , viral disease , surgery , virus
Congenital cytomegalovirus (CMV) infection is a leading cause of hearing loss and neurologic disabilities in children worldwide. Infants with symptomatic congenital CMV infection at birth are at significantly increased risk for developing adverse long-term outcomes. The vast majority of infants with congenital CMV infection have no clinical findings at birth (asymptomatic infants), and about 10%-15% of these children develop long-term sequelae. Currently, predictors of adverse outcome in asymptomatic congenital CMV infection are not known, and it is important that future studies address this issue.
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