High Frequency of False-Positive Hepatitis C Virus Enzyme-Linked Immunosorbent Assay in Rakai, Uganda | Zendy

Caroline E. Mullis | Zendy; Oliver Laeyendecker | Zendy; Steven J. Reynolds | Zendy; Ponsiano Ocama | Zendy; Jeffrey Quinn | Zendy; Boaz Iga | Zendy; RH Gray | Zendy; Gregory D. Kirk | Zendy; David L. Thomas | Zendy; Thomas C. Quinn | Zendy; Lara Stabinski | Zendy

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High Frequency of False-Positive Hepatitis C Virus Enzyme-Linked Immunosorbent Assay in Rakai, Uganda

Author(s) -

Caroline E. Mullis,

Oliver Laeyendecker,

Steven J. Reynolds,

Ponsiano Ocama,

Jeffrey Quinn,

Boaz Iga,

RH Gray,

Gregory D. Kirk,

David L. Thomas,

Thomas C. Quinn,

Lara Stabinski

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit602

Subject(s) - medicine , hepatitis c virus , virology , antibody , hepatitis c , virus , enzyme , immunology , biology , biochemistry

The prevalence of hepatitis C virus (HCV) infection in sub-Saharan Africa remains unclear. We tested 1000 individuals from Rakai, Uganda, with the Ortho version 3.0 HCV enzyme-linked immunosorbent assay. All serologically positive samples were tested for HCV RNA. Seventy-six of the 1000 (7.6%) participants were HCV antibody positive; none were confirmed by detection of HCV RNA.

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