Invasive Haemophilus influenzae Type b Disease in England and Wales: Who Is at Risk After 2 Decades of Routine Childhood Vaccination? | Zendy

Sarah Collins | Zendy; Mary Ramsay | Zendy; Helen Campbell | Zendy; Mary Slack | Zendy; Shamez Ladhani | Zendy

Open Access

Invasive Haemophilus influenzae Type b Disease in England and Wales: Who Is at Risk After 2 Decades of Routine Childhood Vaccination?

Author(s) -

Sarah Collins,

Mary Ramsay,

Helen Campbell,

Mary Slack,

Shamez Ladhani

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit579

Subject(s) - medicine , vaccination , pediatrics , incidence (geometry) , case fatality rate , epidemiology , hib vaccine , disease , conjugate vaccine , epiglottitis , haemophilus influenzae , pneumonia , public health , meningitis , immunization , immunology , antibiotics , pathology , physics , microbiology and biotechnology , antigen , optics , biology

The introduction of the Haemophilus influenzae serotype b (Hib) conjugate vaccine into national immunization has led to rapid and sustained declines in invasive Hib disease incidence across all age groups. In industrialized countries with established Hib vaccination programs, however, little is known about individuals who develop invasive Hib disease. This study describes the epidemiology of invasive Hib disease in England and Wales during 2000-2012 and the clinical characteristics of laboratory-confirmed Hib cases diagnosed during 2009-2012.

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