Risk of Liver Decompensation Among HIV/Hepatitis C Virus-Coinfected Individuals With Advanced Fibrosis: Implications for the Timing of Therapy | Zendy

Juan Macı́as | Zendy; Manuel Márquez | Zendy; Francisco Téllez | Zendy; Dolores Merino | Zendy; Patricia Jiménez-Aguilar | Zendy; Luís F. LópezCortés | Zendy; Enrique Ortega | Zendy; M. A. von Wichmann | Zendy; Antonio Rivero | Zendy; M.J. Mancebo | Zendy; J Santos | Zendy; M. Pérez-Pérez | Zendy; Ignacio Suárez-Lozano | Zendy; Alberto Romero-Palacios | Zendy; Almudena Torres-Cornejo | Zendy; Juan A. Pineda | Zendy

Open Access

Risk of Liver Decompensation Among HIV/Hepatitis C Virus-Coinfected Individuals With Advanced Fibrosis: Implications for the Timing of Therapy

Author(s) -

Juan Macı́as,

Manuel Márquez,

Francisco Téllez,

Dolores Merino,

Patricia Jiménez-Aguilar,

Luís F. LópezCortés,

Enrique Ortega,

M. A. von Wichmann,

Antonio Rivero,

M.J. Mancebo,

J Santos,

M. Pérez-Pérez,

Ignacio Suárez-Lozano,

Alberto Romero-Palacios,

Almudena Torres-Cornejo,

Juan A. Pineda

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit537

Subject(s) - medicine , hepatitis c virus , gastroenterology , hepatitis c , decompensation , cirrhosis , confidence interval , fibrosis , liver biopsy , serostatus , surgery , viral load , biopsy , immunology , human immunodeficiency virus (hiv) , virus

Most human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-infected patients who are currently receiving boceprevir or telaprevir-based therapy against HCV show cirrhosis. However, the risk of liver decompensation (DC) among HIV/HCV-coinfected patients with stage 3 fibrosis in the short term could be high enough to not allow delays. We aimed at assessing the risk of DC among HIV/HCV-coinfected individuals with advanced fibrosis (F3-F4).

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