Impact of Routine Systematic Polymerase Chain Reaction Testing on Case Finding for Legionnaires’ Disease: A Pre–Post Comparison Study | Zendy

David R. Murdoch | Zendy; Roslyn G. Podmore | Zendy; Trevor P. Anderson | Zendy; Kevin Barratt | Zendy; Michael J. Maze | Zendy; Kathryn French | Zendy; Sheryl A. Young | Zendy; Stephen T. Chambers | Zendy; Anja Werno | Zendy

Open Access

Impact of Routine Systematic Polymerase Chain Reaction Testing on Case Finding for Legionnaires’ Disease: A Pre–Post Comparison Study

Author(s) -

David R. Murdoch,

Roslyn G. Podmore,

Trevor P. Anderson,

Kevin Barratt,

Michael J. Maze,

Kathryn French,

Sheryl A. Young,

Stephen T. Chambers,

Anja Werno

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit504

Subject(s) - legionnaires' disease , medicine , polymerase chain reaction , disease , intensive care medicine , pathology , legionella pneumophila , genetics , bacteria , biology , gene

Legionnaires' disease cannot be clinically or radiographically distinguished from other causes of pneumonia, and specific tests are required to make the diagnosis. Currently, testing occurs erratically and, instead, clinicians rely on empiric treatment strategies and ignore public health implications of the diagnosis. We aimed to measure the increase in case detection of Legionnaires' disease following the introduction of routine polymerase chain reaction (PCR) testing of respiratory specimens. PCR is the most sensitive diagnostic tool for Legionnaires' disease.

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