Use of Multilocus Variable Number of Tandem Repeats Analysis Genotyping to Determine the Role of Asymptomatic Carriers in Clostridium difficile Transmission
Author(s) -
Scott Curry,
Carlene A. Muto,
Jessica L. Schlackman,
A. William Pasculle,
Kathleen A. Shutt,
Jane W. Marsh,
Lee H. Harrison
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit475
Subject(s) - multiple loci vntr analysis , clostridium difficile , carriage , asymptomatic carrier , variable number tandem repeat , genotyping , medicine , transmission (telecommunications) , tandem repeat , multilocus sequence typing , asymptomatic , microbiology and biotechnology , subtyping , virology , genotype , biology , genetics , pathology , antibiotics , electrical engineering , genome , gene , computer science , programming language , engineering
Previous studies have suggested that asymptomatic carriers of toxigenic Clostridium difficile are a source of hospital-associated (HA) infections. Multilocus variable number of tandem repeats analysis (MLVA) is a highly discriminatory molecular subtyping tool that helps to determine possible transmission sources.
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