Risk of QTc Prolongation in a Cohort of Opioid-Dependent HIV-Infected Patients on Methadone Maintenance Therapy
Author(s) -
Gabriel Vallecillo,
Sergi Mojal,
Albert Roquer,
Diana Martínez,
Paolo Rossi,
Francina Fonseca,
Roberto Muga,
Marta Torrens
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit467
Subject(s) - medicine , qt interval , methadone , torsades de pointes , opioid , cohort , methadone maintenance , cohort study , anesthesia , receptor
Concern regarding the QTc interval in human immunodeficiency virus (HIV)-infected patients has been growing in recent years, and cases of prolonged QTc interval and torsades de pointes have been described in HIV-infected patients on methadone therapy. This study aimed to determine the prevalence and factors associated with long QTc interval in a cohort of opioid-dependent HIV-infected patients on methadone maintenance therapy.
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