Role of IL28B Gene Polymorphism and Cell-Mediated Immunity in Spontaneous Resolution of Acute Hepatitis C | Zendy

Enea Spada | Zendy; Pietro Amoroso | Zendy; Gloria Taliani | Zendy; Ornella Zuccaro | Zendy; Piergiorgio Chiriacò | Zendy; Patrizia Maio | Zendy; Giuseppe Di Maio | Zendy; Maria Luisa Esposito | Zendy; Mariano Corrado | Zendy; Roberto Rinaldi | Zendy; P Bellissima | Zendy; Maria Elena Tosti | Zendy; Paola Del Porto | Zendy; Ruggiero Francavilla | Zendy; Vincenzo Mellace | Zendy; Anna Rosa Garbuglia | Zendy; Antonella Folgori | Zendy; Alfonso Mele | Zendy; Salvatore Buonocore | Zendy; Gennaro Lettieri | Zendy; Paola Pierri | Zendy; Lucio Cosco | Zendy; Teresa Ferraro | Zendy; Paola Scognamiglio | Zendy; Maria Rosaria Capobianchi | Zendy; U Baldi | Zendy; Franco Montesano | Zendy; Giulia Audino | Zendy; Caterina De Stefano | Zendy; A Caterini | Zendy; Mario Cuccia | Zendy; G. Girelli | Zendy; Paola Perrone | Zendy; Luca Laurenti | Zendy; Enza Piccolella | Zendy; Cristiano Scottà | Zendy; Riccardo Cortese | Zendy; Alfredo Nicosia | Zendy; Alessandra Vitelli | Zendy

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Role of IL28B Gene Polymorphism and Cell-Mediated Immunity in Spontaneous Resolution of Acute Hepatitis C

Author(s) -

Enea Spada,

Pietro Amoroso,

Gloria Taliani,

Ornella Zuccaro,

Piergiorgio Chiriacò,

Patrizia Maio,

Giuseppe Di Maio,

Maria Luisa Esposito,

Mariano Corrado,

Roberto Rinaldi,

P Bellissima,

Maria Elena Tosti,

Paola Del Porto,

Ruggiero Francavilla,

Vincenzo Mellace,

Anna Rosa Garbuglia,

Antonella Folgori,

Alfonso Mele,

Salvatore Buonocore,

Gennaro Lettieri,

Paola Pierri,

Lucio Cosco,

Teresa Ferraro,

Paola Scognamiglio,

Maria Rosaria Capobianchi,

U Baldi,

Franco Montesano,

Giulia Audino,

Caterina De Stefano,

A Caterini,

Mario Cuccia,

G. Girelli,

Paola Perrone,

Luca Laurenti,

Enza Piccolella,

Cristiano Scottà,

Riccardo Cortese,

Alfredo Nicosia,

Alessandra Vitelli

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit402

Subject(s) - genotype , medicine , odds ratio , gastroenterology , snp , immunology , confidence interval , single nucleotide polymorphism , biology , gene , genetics

A single-nucleotide polymorphism (SNP; rs12979860) near the IL28B gene has been associated with spontaneous and treatment-induced hepatitis C virus clearance. We investigated predictors of spontaneous disease resolution in a cohort of patients with acute hepatitis C (AHC), analyzing epidemiological, clinical and virological parameters together with IL28B.rs12979860 genotypes and cell-mediated immunity (CMI).

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