The Serum Galactomannan Index Predicts Mortality in Hematopoietic Stem Cell Transplant Recipients With Invasive Aspergillosis
Author(s) -
Cynthia E. Fisher,
Anne M. Stevens,
Wendy M. Leisenring,
Steven A. Pergam,
Michael Boeckh,
Tobias M. Hohl
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit393
Subject(s) - galactomannan , medicine , aspergillosis , bronchoalveolar lavage , hematopoietic stem cell transplantation , immunology , haematopoiesis , hematopoietic cell , gastroenterology , transplantation , lung , stem cell , genetics , biology
We examined the relationship between serum and bronchoalveolar lavage (BAL) galactomannan index (GMI) values and mortality in allogeneic hematopoietic cell transplant recipients with invasive pulmonary aspergillosis. Using a clinical sign and symptom-initiated approach, we found that the serum but not the BAL GMI level correlated with 42- and 180-day patient mortality.
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