Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles
Author(s) -
Jan W. M. van der Linden,
Simone M. T. Camps,
Greetje A. Kampinga,
Jan P. Arends,
Y. J. Debets-Ossenkopp,
P. J. A. Haas,
Bart Rijnders,
Ed J. Kuijper,
Frank H. van Tiel,
János Varga,
Anna Karawajczyk,
Jan Zoll,
Willem J. G. Melchers,
Paul E. Verweij
Publication year - 2013
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cit320
Subject(s) - voriconazole , aspergillus fumigatus , azole , aspergillosis , microbiology and biotechnology , aspergillus , medicine , agar dilution , biology , minimum inhibitory concentration , antifungal , immunology , antibiotics
Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the management of patients with Aspergillus-related diseases. Selection of azole resistance may occur through exposure to azole fungicides in the environment. In the Netherlands a surveillance network was used to investigate the epidemiology of resistance selection in A. fumigatus.
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