Multiple Contributory Factors to the Age Distribution of Disease Cases: A Modeling Study in the Context of Influenza A(H3N2v) | Zendy

Manoj Gambhir | Zendy; David L. Swerdlow | Zendy; Lyn Finelli | Zendy; Maria D. Van Kerkhove | Zendy; Matthew Biggerstaff | Zendy; Simon Cauchemez | Zendy; Neil M. Ferguson | Zendy

Open Access

Multiple Contributory Factors to the Age Distribution of Disease Cases: A Modeling Study in the Context of Influenza A(H3N2v)

Author(s) -

Manoj Gambhir,

David L. Swerdlow,

Lyn Finelli,

Maria D. Van Kerkhove,

Matthew Biggerstaff,

Simon Cauchemez,

Neil M. Ferguson

Publication year - 2013

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cit298

Subject(s) - medicine , context (archaeology) , disease , biology , paleontology

In late 2011 and early 2012, 13 cases of human influenza resulted from infection with a novel triple reassortant swine-origin influenza virus, influenza A (H3N2) variant. This variant was notable for its inclusion of the matrix gene from the 2009 influenza A(H1N1) pandemic virus. While most of these confirmed cases were among children, the transmission potential and likely age-dependent susceptibility to the virus was unknown. Preliminary serologic studies indicated that very young children have less protection than older children and adults.

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